Magnolol Reduces Glutamate-Induced Neuronal Excitotoxicity and Protects against Permanent Focal Cerebral Ischemia Up to 4 Hours

Neuroprotective efficacy of magnolol, 5,5′-dially-2,2′-dihydroxydiphenyl, was investigated in a model of stroke and cultured neurons exposed to glutamate-induced excitotoxicity. Rats were subjected to permanent middle cerebral artery occlusion (pMCAO). Magnolol or vehicle was administered intraperit...

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Bibliografiske detaljer
Main Authors: Lee, Wei-Ting, Lin, Miao-Hui, Lee, E-Jian, Hung, Yu-Chang, Tai, Shih-Huang, Chen, Hung-Yi, Chen, Tsung-Ying, Wu, Tian-Shung
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392264/
https://ncbi.nlm.nih.gov/pubmed/22808077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039952
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