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A Study on the Effect of Surface Lysine to Arginine Mutagenesis on Protein Stability and Structure Using Green Fluorescent Protein

Two positively charged basic amino acids, arginine and lysine, are mostly exposed to protein surface, and play important roles in protein stability by forming electrostatic interactions. In particular, the guanidinium group of arginine allows interactions in three possible directions, which enables...

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Autori principali: Sokalingam, Sriram, Raghunathan, Govindan, Soundrarajan, Nagasundarapandian, Lee, Sun-Gu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392243/
https://ncbi.nlm.nih.gov/pubmed/22792305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040410
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