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Comprehensive Carrier Screening and Molecular Diagnostic Testing for Recessive Childhood Diseases

Of 7,028 disorders with suspected Mendelian inheritance, 1,139 are recessive and have an established molecular basis. Although individually uncommon, Mendelian diseases collectively account for ~20% of infant mortality and ~18% of pediatric hospitalizations. Molecular diagnostic testing is currently...

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Bibliografische gegevens
Hoofdauteur: Kingsmore, Stephen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392137/
https://ncbi.nlm.nih.gov/pubmed/22872815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/4f9877ab8ffa9
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