Nicotinic Acetylcholine Receptor Stability at the NMJ Deficient in α-Syntrophin In Vivo

α-Syntrophin (α-syn), a scaffold protein, links signaling molecules to the dystrophin–glycoprotein complex. Absence of α-syn from the DGC is known to lead to structurally aberrant neuromuscular junctions (NMJs) with few acetylcholine receptors (AChRs) clustered at synaptic sites. Using α-syn knock-o...

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Main Authors: Martinez-Pena y Valenzuela, Isabel, Mouslim, Chakib, Pires-Oliveira, Marcelo, Adams, Marvin E., Froehner, Stanley C., Akaaboune, Mohammed
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392018/
https://ncbi.nlm.nih.gov/pubmed/22031904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4038-11.2011
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