Fatty acids-stress attenuates gluconeogenesis induction and glucose production in primary hepatocytes

BACKGROUND: Hepatic gluconeogenesis tightly controls blood glucose levels in healthy individuals, yet disorders of fatty acids (FAs) oxidation are characterized by hypoglycemia. We studied the ability of free-FAs to directly inhibit gluconeogenesis, as a novel mechanism that elucidates the hypoglyce...

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Hlavní autoři: Budick-Harmelin, Noga, Anavi, Sarit, Madar, Zecharia, Tirosh, Oren
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391994/
https://ncbi.nlm.nih.gov/pubmed/22676303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-11-66
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