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Attenuating the Endoplasmic Reticulum Stress Response Improves Functional Recovery After Spinal Cord Injury

Activation of the unfolded protein response (UPR) is involved in the pathogenesis of numerous CNS myelin abnormalities; yet, its direct role in traumatic spinal cord injury (SCI)-induced demyelination is not known. The UPR is an evolutionarily conserved cell defense mechanism initiated to restore en...

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Bibliographic Details
Main Authors: OHRI, SUJATA SARASWAT, MADDIE, MELISSA A., ZHAO, YONGMEI, QIU, MENGSHENG S., HETMAN, MICHAL, WHITTEMORE, SCOTT R.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391751/
https://ncbi.nlm.nih.gov/pubmed/21638341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21191
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