Phosphodiesterase-5 (PDE5) is a Therapeutic Target for Peripheral Neuropathy in Diabetic Mice

Peripheral neuropathy is a common and major complication of diabetes, the underlying mechanisms of which are not fully understood. Using a mouse model of type II diabetes, the present study investigated the role of phosphodiesterase-5 (PDE5) in peripheral neuropathy. BKS.Cg-m+/+Lepr(db)/J (db/db) mi...

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Hauptverfasser: Wang, Lei, Chopp, Michael, Szalad, Alexandra, Liu, Zhongwu, Bolz, Marianne, Ãlvarez, Francisco Moniche, Lu, Mei, Zhang, Li, Cui, Yisheng, Zhang, Rui Lan, Zhang, Zheng Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391742/
https://ncbi.nlm.nih.gov/pubmed/21820491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2011.07.039
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