Alternaria alternata allergen, Alt a 1 - a unique, β-barrel protein dimer exclusively found in fungi

BACKGROUND: Alternaria is one of the most common molds associated with allergic diseases and 80% of Alternaria-sensitive patients produce IgE antibodies to a major protein allergen, Alt a 1. The structure and function of Alt a 1 is unknown. OBJECTIVE: To obtain a high resolution structure of Alt a 1...

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Main Authors: Chruszcz, Maksymilian, Chapman, Martin D., Osinski, Tomasz, Solberg, Robert, Demas, Matthew, Porebski, Przemyslaw J., Majorek, Karolina A., Pomés, Anna, Minor, Wladek
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391610/
https://ncbi.nlm.nih.gov/pubmed/22664167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.03.047
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