Lack of Association Between TLR4 rs4986790 Polymorphism and Risk of Cardiovascular Disease in Patients with Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with increased cardiovascular (CV) mortality. Toll-like receptor-4 (TLR4) activates the innate immune response via NF-kB pathway and mitogen-activated protein kinase signaling, leading to expression of proinflammatory cytokines a...

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Autores principales: García-Bermúdez, Mercedes, López-Mejías, Raquel, González-Juanatey, Carlos, Castañeda, Santos, Miranda-Filloy, José A., Blanco, Ricardo, Fernández-Gutiérrez, Benjamín, Balsa, Alejandro, González-Alvaro, Isidoro, Gómez-Vaquero, Carmen, Llorca, Javier, Martín, Javier, González-Gay, Miguel A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2012
Materias:
Original Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391495/
https://ncbi.nlm.nih.gov/pubmed/22360682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2011.1582
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