The Role of LEF1 in Endometrial Gland Formation and Carcinogenesis

Endometrial carcinoma is the most common gynecologic cancer, yet the mechanisms underlying this disease process are poorly understood. We hypothesized that Lef1 is required for endometrial gland formation within the uterus and is overexpressed in endometrial cancer. Using Lef1 knockout (KO) mice, we...

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Autori principali: Shelton, Dawne N., Fornalik, Hubert, Neff, Traci, Park, Soo Yeun, Bender, David, DeGeest, Koen, Liu, Xiaoming, Xie, Weiliang, Meyerholz, David K., Engelhardt, John F., Goodheart, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391280/
https://ncbi.nlm.nih.gov/pubmed/22792274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040312
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