Decreased Circulating C3 Levels and Mesangial C3 Deposition Predict Renal Outcome in Patients with IgA Nephropathy

BACKGROUND AND AIMS: Mesangial C3 deposition is frequently observed in patients with IgA nephropathy (IgAN). However, the role of complement in the pathogenesis or progression of IgAN is uncertain. In this observational cohort study, we aimed to identify the clinical implications of circulating C3 l...

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Autors principals: Kim, Seung Jun, Koo, Hyang Mo, Lim, Beom Jin, Oh, Hyung Jung, Yoo, Dong Eun, Shin, Dong Ho, Lee, Mi Jung, Doh, Fa Mee, Park, Jung Tak, Yoo, Tae-Hyun, Kang, Shin-Wook, Choi, Kyu Hun, Jeong, Hyeon Joo, Han, Seung Hyeok
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391269/
https://ncbi.nlm.nih.gov/pubmed/22792353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040495
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