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Binding of Phytopolyphenol Piceatannol Disrupts β/γ Subunit Interactions and Rate-limiting Step of Steady-state Rotational Catalysis in Escherichia coli F(1)-ATPase

In observations of single molecule behavior under V(max) conditions with minimal load, the F(1) sector of the ATP synthase (F-ATPase) rotates through continuous cycles of catalytic dwells (∼0.2 ms) and 120° rotation steps (∼0.6 ms). We previously established that the rate-limiting transition step oc...

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Detalhes bibliográficos
Main Authors: Sekiya, Mizuki, Nakamoto, Robert K., Nakanishi-Matsui, Mayumi, Futai, Masamitsu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391159/
https://ncbi.nlm.nih.gov/pubmed/22582396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.374868
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