Regulatory Domain Determinants That Control PKD1 Activity

The canonical pathway for protein kinase D1 (PKD1) activation by growth factor receptors involves diacylglycerol binding to the C1 domain and protein kinase C-dependent phosphorylation at the activation loop. PKD1 then autophosphorylates at Ser(916), a modification frequently used as a surrogate mar...

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Detaylı Bibliyografya
Asıl Yazarlar: Rybin, Vitalyi O., Guo, Jianfen, Harleton, Erin, Zhang, Fan, Steinberg, Susan F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2012
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391082/
https://ncbi.nlm.nih.gov/pubmed/22582392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.379719
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