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Soy Isoflavones Have an Antiestrogenic Effect and Alter Mammary Promoter Hypermethylation in Healthy Premenopausal Women

We determined if soy isoflavones have dose-related estrogenic and methylation effects. Thirty-four healthy premenopausal women were randomized to 40 mg or 140 mg isoflavones daily through one menstrual cycle. Breast specific and systemic estrogenic effects were assessed measuring the estrogenic mark...

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Autores principales: Qin, Wenyi, Zhu, Weizhu, Shi, Huidong, Hewett, John E., Ruhlen, Rachel L., MacDonald, Ruth S., Rottinghaus, George E., Chen, Yin-Chieh, Sauter, Edward R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390914/
https://ncbi.nlm.nih.gov/pubmed/19235040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01635580802404196
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