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N–N Bond-Forming Cyclization for the One-Pot Synthesis of N-Aryl[3,4-d]pyrazolopyrimidines

[Image: see text] An efficient one-pot synthesis of N-aryl[3,4-d]pyrazolopyrimidines in good yield and under mild reaction conditions is described. By exploiting electron-deficient hydroxylamines, the substituted oxime products were formed with very high E-diastereoselectivity. The key step utilizes...

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Detalhes bibliográficos
Main Authors: Evans, Lindsay E., Cheeseman, Matthew D., Jones, Keith
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390909/
https://ncbi.nlm.nih.gov/pubmed/22734502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol301561a
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