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Novel mitochondrial targets for neuroprotection
Mitochondrial dysfunction contributes to the pathophysiology of acute neurologic disorders and neurodegenerative diseases. Bioenergetic failure is the primary cause of acute neuronal necrosis, and involves excitotoxicity-associated mitochondrial Ca(2+) overload, resulting in opening of the inner mem...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390821/ https://ncbi.nlm.nih.gov/pubmed/22453628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.32 |
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