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Evidence of the Involvement of O-GlcNAc-modified Human RNA Polymerase II CTD in Transcription in Vitro and in Vivo

The RNA polymerase II C-terminal domain (CTD), which serves as a scaffold to recruit machinery involved in transcription, is modified post-translationally. Although the O-GlcNAc modification of RNA polymerase II CTD was documented in 1993, its functional significance remained obscure. We show that O...

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Bibliografski detalji
Glavni autori: Ranuncolo, Stella M., Ghosh, Salil, Hanover, John A., Hart, Gerald W., Lewis, Brian A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390630/
https://ncbi.nlm.nih.gov/pubmed/22605332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.330910
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