Role of Deleted in Breast Cancer 1 (DBC1) Protein in SIRT1 Deacetylase Activation Induced by Protein Kinase A and AMP-activated Protein Kinase

The NAD(+)-dependent deacetylase SIRT1 is a key regulator of several aspects of metabolism and aging. SIRT1 activation is beneficial for several human diseases, including metabolic syndrome, diabetes, obesity, liver steatosis, and Alzheimer disease. We have recently shown that the protein deleted in...

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Autors principals: Nin, Veronica, Escande, Carlos, Chini, Claudia C., Giri, Shailendra, Camacho-Pereira, Juliana, Matalonga, Jonathan, Lou, Zhenkun, Chini, Eduardo N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390625/
https://ncbi.nlm.nih.gov/pubmed/22553202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365874
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