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A Competitive Inhibitor That Reduces Recruitment of Androgen Receptor to Androgen-responsive Genes
The androgen receptor (AR) has a critical role in the growth and progression of androgen-dependent and castration-resistant prostate cancers. To identify novel inhibitors of AR transactivation that block growth of prostate cancer cells, a luciferase-based high-throughput screen of ∼160,000 small mol...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390614/ https://ncbi.nlm.nih.gov/pubmed/22589544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.344671 |
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