Inducible and Conditional Deletion of Extracellular Signal-regulated Kinase 5 Disrupts Adult Hippocampal Neurogenesis

Recent studies have led to the exciting idea that adult-born neurons in the dentate gyrus of the hippocampus may play a role in hippocampus-dependent memory formation. However, signaling mechanisms that regulate adult hippocampal neurogenesis are not well defined. Here we report that extracellular s...

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Autori principali: Pan, Yung-Wei, Zou, Junhui, Wang, Wenbin, Sakagami, Hiroyuki, Garelick, Michael G., Abel, Glen, Kuo, Chay T., Storm, Daniel R., Xia, Zhengui
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390609/
https://ncbi.nlm.nih.gov/pubmed/22645146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.344762
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