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Quantifying and Analyzing the Network Basis of Genetic Complexity

Genotype-to-phenotype maps exhibit complexity. This genetic complexity is mentioned frequently in the literature, but a consistent and quantitative definition is lacking. Here, we derive such a definition and investigate its consequences for model genetic systems. The definition equates genetic comp...

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Autori principali: Thompson, Ethan G., Galitski, Timothy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390359/
https://ncbi.nlm.nih.gov/pubmed/22792055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002583
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