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Oscillation in Cycle Length Induces Transient Discordant and Steady-State Concordant Alternans in the Heart

Alternans is a beat-to-beat alternation of the cardiac action potential duration (APD) or intracellular calcium (Ca(i)) transient. In cardiac tissue, alternans can be spatially concordant or discordant, of which the latter has been shown to increase dispersion of repolarization and promote a substra...

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Autori principali: Weinberg, Seth H., Tung, Leslie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390356/
https://ncbi.nlm.nih.gov/pubmed/22792346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040477
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