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Antibacterial Activity and Mechanism of a Scorpion Venom Peptide Derivative In Vitro and In Vivo

BmKn2 is an antimicrobial peptide (AMP) characterized from the venom of scorpion Mesobuthus martensii Karsch by our group. In this study, Kn2-7 was derived from BmKn2 to improve the antibacterial activity and decrease hemolytic activity. Kn2-7 showed increased inhibitory activity against both Gram-p...

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Bibliografiske detaljer
Main Authors: Cao, Luyang, Dai, Chao, Li, Zhongjie, Fan, Zheng, Song, Yu, Wu, Yingliang, Cao, Zhijian, Li, Wenxin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390344/
https://ncbi.nlm.nih.gov/pubmed/22792229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040135
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