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Microbead-Induced Ocular Hypertensive Mouse Model for Screening and Testing of Aqueous Production Suppressants for Glaucoma
PURPOSE. To characterize the microbead-induced ocular hypertension (OHT) mouse model and investigate its potential use for preclinical screening and evaluation of ocular hypotensive agents, we tested the model's responses to major antiglaucoma drugs. METHODS. Adult C57BL/6J mice were induced to...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Association for Research in Vision and Ophthalmology
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390181/ https://ncbi.nlm.nih.gov/pubmed/22599582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-9814 |
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