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Microbead-Induced Ocular Hypertensive Mouse Model for Screening and Testing of Aqueous Production Suppressants for Glaucoma

PURPOSE. To characterize the microbead-induced ocular hypertension (OHT) mouse model and investigate its potential use for preclinical screening and evaluation of ocular hypotensive agents, we tested the model's responses to major antiglaucoma drugs. METHODS. Adult C57BL/6J mice were induced to...

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Detalhes bibliográficos
Main Authors: Yang, Qiang, Cho, Kin-Sang, Chen, Huihui, Yu, Dekuang, Wang, Wan-Heng, Luo, Gang, Pang, Iok-Hou, Guo, Wenyi, Chen, Dong Feng
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390181/
https://ncbi.nlm.nih.gov/pubmed/22599582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-9814
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