MIF: a down-regulator of early T cell-dependent IFN-γ responses in Plasmodium chabaudi adami (DK) infected mice

Neutralization of macrophage migration inhibitory factor (MIF) increases anti-tumor cytotoxic T cell responses in vivo and IFN-γ responses in vitro, suggesting a plausible regulatory role for MIF in T cell activation. Considering that IFN-γ production by CD4(+) T cells is pivotal to resolve murine m...

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Autors principals: Tshikudi Malu, Diane, Bélanger, Benoit, Desautels, François, Kelendji, Karine, Dalko, Esther, Sanchez-Dardon, Jaime, Leng, Lin, Bucala, Richard, Satoskar, Abhay, Scorza, Tatiana
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390021/
https://ncbi.nlm.nih.gov/pubmed/21518974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003355
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