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Antidiabetic Drug Metformin Suppresses Endotoxin-Induced Uveitis in Rats
PURPOSE. To investigate the therapeutic effects of metformin, a commonly used antidiabetic drug, in preventing endotoxin-induced uveitis (EIU) in rats. METHODS. EIU in Lewis rats was developed by subcutaneous injection of lipopolysaccharide (LPS; 150 μg). Metformin (300 mg/kg body weight, intraperit...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The Association for Research in Vision and Ophthalmology
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390006/ https://ncbi.nlm.nih.gov/pubmed/22562515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-9432 |
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