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D-cycloserine facilitation of cognitive behavioral therapy for delusions in schizophrenia

Glutamatergic N-methyl-D-aspartate (NMDA) receptor hypofunction has been proposed as a mechanism underlying psychosis. D-cycloserine, a partial agonist at the glycine site of the NMDA receptor, enhances learning in animal models, although tachyphylaxis develops with repeated dosing. Once-weekly dosi...

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Detalhes bibliográficos
Main Authors: Gottlieb, Jennifer D., Cather, Corinne, Shanahan, Meghan, Creedon, Timothy, Macklin, Eric A., Goff, Donald C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389827/
https://ncbi.nlm.nih.gov/pubmed/21723096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2011.05.029
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