Everolimus tablets for patients with subependymal giant cell astrocytoma

INTRODUCTION: Better understanding of aberrantly active molecular pathways in tumors offers potential to develop more specific and less toxic therapies. Abnormal mammalian target of rapamycin (mTOR) complex signaling and defects in TSC1 and TSC2 have been associated with the development of sub-epend...

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Autori principali: Turner, Scott G, Peters, Katherine B, Vredenburgh, James J, Desjardins, Annick, Friedman, Henry S, Reardon, David A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389821/
https://ncbi.nlm.nih.gov/pubmed/21806479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14656566.2011.601742
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