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Fast computation for genome-wide association studies using boosted one-step statistics

Motivation: Statistical analyses of genome-wide association studies (GWAS) require fitting large numbers of very similar regression models, each with low statistical power. Taking advantage of repeated observations or correlated phenotypes can increase this statistical power, but fitting the more co...

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Detalhes bibliográficos
Main Authors: Voorman, Arend, Rice, Ken, Lumley, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389774/
https://ncbi.nlm.nih.gov/pubmed/22592383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts291
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