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iFad: an integrative factor analysis model for drug-pathway association inference(†)

Motivation: Pathway-based drug discovery considers the therapeutic effects of compounds in the global physiological environment. This approach has been gaining popularity in recent years because the target pathways and mechanism of action for many compounds are still unknown, and there are also some...

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Detalhes bibliográficos
Main Authors: Ma, Haisu, Zhao, Hongyu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389771/
https://ncbi.nlm.nih.gov/pubmed/22581178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts285
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