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Exploring single-sample SNP and INDEL calling with whole-genome de novo assembly
Motivation: Eugene Myers in his string graph paper suggested that in a string graph or equivalently a unitig graph, any path spells a valid assembly. As a string/unitig graph also encodes every valid assembly of reads, such a graph, provided that it can be constructed correctly, is in fact a lossles...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3389770/ https://ncbi.nlm.nih.gov/pubmed/22569178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts280 |
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