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Endothelin-1 and Norepinephrine Overflow from Cardiac Sympathetic Nerve Endings in Myocardial Ischemia

In protracted myocardial ischemia, sympathetic activation with carrier-mediated excessive norepinephrine (NE) release from its nerve endings due to reversal of NE transporter in an outward direction is a prominent cause of arrhythmias and cardiac dysfunction. Endothelin-1 (ET-1) and its receptors ar...

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Autors principals: Tawa, Masashi, Yamamoto, Satoshi, Ohkita, Mamoru, Matsumura, Yasuo
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389657/
https://ncbi.nlm.nih.gov/pubmed/22792506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/789071
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