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QTc prolongation is associated with impaired right ventricular function and predicts mortality in pulmonary hypertension

BACKGROUND: In rodent models of pulmonary hypertension (PH) and right ventricular hypertrophy (RVH), the QTc interval is prolonged, reflecting downregulation of repolarizing Kv channels in RV myocytes. The significance of QTc prolongation in human PH is unknown. We hypothesized that QTc prolongation...

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Detalhes bibliográficos
Main Authors: Rich, Jonathan D., Thenappan, Thenappan, Freed, Benjamin, Patel, Amit R., Thisted, Ronald A., Childers, Rory, Archer, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389574/
https://ncbi.nlm.nih.gov/pubmed/22459397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2012.03.071
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