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In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system

Although significant progress has been made in understanding the importance of Wnt signaling in the initiation of colorectal cancer, less is known about responses that accompany the reversal of oncogenic Wnt signaling. The aim of this study was to analyze in vivo and in vitro responses to an ‘ideal’...

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Main Authors: Jardé, Thierry, Evans, Rebecca J, McQuillan, Karina L, Parry, Lee, Feng, Gui Jie, Alvares, Bernardo, Clarke, Alan R, Dale, Trevor C
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389516/
https://ncbi.nlm.nih.gov/pubmed/22469981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.103
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