Δn89β-Catenin Induces Precocious Development, Differentiation, and Neoplasia in Mammary Gland

To investigate the role of β-catenin in mammary gland development and neoplasia, we expressed a stabilized, transcriptionally active form of β-catenin lacking the NH(2)-terminal 89 amino acids (ΔN89β-catenin) under the control of the mouse mammary tumor virus long terminal repeat. Our results show t...

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Bibliographic Details
Main Authors: Imbert, Alexandra, Eelkema, Rachel, Jordan, Sara, Feiner, Helen, Cowin, Pamela
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2001
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190562/
https://ncbi.nlm.nih.gov/pubmed/11331306
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