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Structural and functional analysis of rare missense mutations in human chorionic gonadotrophin β-subunit

Heterodimeric hCG is one of the key hormones determining early pregnancy success. We have previously identified rare missense mutations in hCGβ genes with potential pathophysiological importance. The present study assessed the impact of these mutations on the structure and function of hCG by applyin...

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Detalhes bibliográficos
Main Authors: Nagirnaja, Liina, Venclovas, Česlovas, Rull, Kristiina, Jonas, Kim C., Peltoketo, Hellevi, Christiansen, Ole B., Kairys, Visvaldas, Kivi, Gaily, Steffensen, Rudi, Huhtaniemi, Ilpo T., Laan, Maris
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389497/
https://ncbi.nlm.nih.gov/pubmed/22554618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gas018
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