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Enhanced COMP catabolism detected in serum of patients with arthritis and animal disease models through a novel capture ELISA

OBJECTIVE: The study aimed determining whether assessment of COMP degradation products could serve as a serological disease course and therapeutic response predictor in arthritis. METHODS: We generated a panel of monoclonal antibodies against COMP fragments and developed a novel capture ELISA for de...

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Detalhes bibliográficos
Main Authors: Lai, Yongjie, Yu, Xiu-Ping, Zhang, Yuying, Tian, Qingyun, Song, Haicheng, Mucignat, Maria Teresa, Perris, Roberto, Samuels, Jonathan, Krasnokutsky, Svetlana, Attur, Mukundan, Greenberg, Jeffrey D., Abramson, Steven B., Di Cesare, Paul E., Liu, Chuanju
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389204/
https://ncbi.nlm.nih.gov/pubmed/22595227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2012.05.003
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