12(S)-Hydroxyheptadeca-5Z,8E,10E-trienoic acid suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity

12(S)-Hydroxyheptadeca-5Z,8E,10E-trienoic acid (12-HHT) is an enzymatic product of prostaglandin H(2) (PGH(2)) derived from cyclooxygenase (COX)-mediated arachidonic acid metabolism. Despite the high level of 12-HHT present in tissues and bodily fluids, its precise function remains largely unknown....

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Bibliographic Details
Main Authors: Lee, Jin-Wook, Ryu, Ho-Cheol, Ng, Yee Ching, Kim, Cheolmin, Wei, Jun-Dong, Sabaratnam, Vikineswary, Kim, Jae-Hong
Format: Artigo
Language:Inglês
Published: Korean Society for Biochemistry and Molecular Biology 2012
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389076/
https://ncbi.nlm.nih.gov/pubmed/22391335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2012.44.6.043
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