Arsenic trioxide induces depolymerization of microtubules in an acute promyelocytic leukemia cell line

BACKGROUND: Arsenic trioxide (As(2)O(3)) is a well-known and effective treatment that can result in clinical remission for patients diagnosed with acute promyelocytic leukemia (APL). The biologic efficacy of As(2)O(3) in APL and solid tumor cells has been explained through its actions on anti-prolif...

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Autori principali: Baek, Jin Ho, Moon, Chang Hoon, Cha, Seung Joo, Lee, Hee Soon, Noh, Eui-Kyu, Kim, Hawk, Won, Jong-Ho, Min, Young Joo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2012
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389058/
https://ncbi.nlm.nih.gov/pubmed/22783356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5045/kjh.2012.47.2.105
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