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Niche-Associated Activation of Rac Promotes the Asymmetric Division of Drosophila Female Germline Stem Cells

BACKGROUND: Drosophila female germline stem cells (GSCs) reside adjacent to a cellular niche that secretes Bone Morphogenetic Protein (BMP) ligands and anchors the GSCs through adherens junctions. The GSCs divide asymmetrically such that one daughter remains in the niche as a GSC, while the other is...

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Detalhes bibliográficos
Main Authors: Lu, Wen, Casanueva, M. Olivia, Mahowald, Anthony P., Kato, Mihoko, Lauterbach, David, Ferguson, Edwin L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389017/
https://ncbi.nlm.nih.gov/pubmed/22802725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001357
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