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Expression, purification, crystallization and preliminary X-ray analysis of the human NORE1 SARAH domain

NORE1 is an important tumour suppressor in human cancers that interacts with the pro-apoptotic protein kinase MST1/2 through SARAH domains. The SARAH domain (residues 366–413) of human NORE1 was expressed in Escherichia coli, purified and crystallized using the hanging-drop vapour-diffusion method....

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Autors principals: Kim, Hye Jin, Hwang, Eunha, Han, Young-Hyun, Choi, Saehae, Lee, Woo Cheol, Kim, Hye-Yeon, Jeon, Young Ho, Cheong, Chaejoon, Cheong, Hae-Kap
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388929/
https://ncbi.nlm.nih.gov/pubmed/22750872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112021744
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