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Improved crystallographic models through iterated local density-guided model deformation and reciprocal-space refinement

An approach is presented for addressing the challenge of model rebuilding after molecular replacement in cases where the placed template is very different from the structure to be determined. The approach takes advantage of the observation that a template and target structure may have local structur...

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Detalhes bibliográficos
Main Authors: Terwilliger, Thomas C., Read, Randy J., Adams, Paul D., Brunger, Axel T., Afonine, Pavel V., Grosse-Kunstleve, Ralf W., Hung, Li-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388814/
https://ncbi.nlm.nih.gov/pubmed/22751672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444912015636
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