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Improved crystallographic models through iterated local density-guided model deformation and reciprocal-space refinement

An approach is presented for addressing the challenge of model rebuilding after molecular replacement in cases where the placed template is very different from the structure to be determined. The approach takes advantage of the observation that a template and target structure may have local structur...

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Détails bibliographiques
Auteurs principaux: Terwilliger, Thomas C., Read, Randy J., Adams, Paul D., Brunger, Axel T., Afonine, Pavel V., Grosse-Kunstleve, Ralf W., Hung, Li-Wei
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388814/
https://ncbi.nlm.nih.gov/pubmed/22751672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444912015636
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