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Prolonged Oxaliplatin Exposure Alters Intracellular Calcium Signaling: A New Mechanism To Explain Oxaliplatin-Associated Peripheral Neuropathy

Oxaliplatin is a platinum based cytotoxic agent commonly used to treat colorectal cancers. Despite its effectiveness, oxaliplatin administration is associated with the development of cold-induced peripheral neuropathy. This potentially permanent side effect is provoked by cold exposure and can range...

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Detalhes bibliográficos
Main Authors: Schulze, Christin, McGowan, Margit, Jordt, Sven, Ehrlich, Barbara E
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388801/
https://ncbi.nlm.nih.gov/pubmed/21859566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clcc.2011.03.010
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