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NR2B-Dependent Plasticity of Adult-Born Granule Cells is Necessary for Context Discrimination

Adult-generated granule cells (GCs) in the dentate gyrus (DG) exhibit a period of heightened plasticity 4–6 weeks postmitosis. However, the functional contribution of this critical window of plasticity to hippocampal neurogenesis and behavior remains unknown. Here, we show that deletion of NR2B-cont...

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Detalhes bibliográficos
Main Authors: Kheirbek, Mazen A., Tannenholz, Lindsay, Hen, René
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388607/
https://ncbi.nlm.nih.gov/pubmed/22723709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1692-12.2012
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