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Biochemical characterization of Metnase's endonuclease activity and its role in NHEJ repair
Metnase (SETMAR) is a SET-transposase fusion protein that promotes non-homologous end joining (NHEJ) repair in humans. Although both SET and the transposase domains were necessary for its function in DSB repair, it is not clear what specific role Metnase plays in the NHEJ. In this study, we show tha...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3388547/ https://ncbi.nlm.nih.gov/pubmed/21491884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200333k |
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