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Biochemical characterization of Metnase's endonuclease activity and its role in NHEJ repair

Metnase (SETMAR) is a SET-transposase fusion protein that promotes non-homologous end joining (NHEJ) repair in humans. Although both SET and the transposase domains were necessary for its function in DSB repair, it is not clear what specific role Metnase plays in the NHEJ. In this study, we show tha...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Beck, Brian D., Lee, Sung-Sook, Williamson, Elizabeth, Hromas, Robert A., Lee, Suk-Hee
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388547/
https://ncbi.nlm.nih.gov/pubmed/21491884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200333k
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