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Separate Roles for Antigen Recognition and Lymph Node Inflammation in CD8(+) Memory T Cell Formation
Priming of naive CD8(+) T cells by pathogens or vaccines generally involves their interaction with Ag-loaded dendritic cells (DCs) in the context of an inflamed lymph node. Lymph node activation fosters DC and T cell encounters and subsequently provides newly primed T cells with nurturing conditions...
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Autores principales: | , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3388546/ https://ncbi.nlm.nih.gov/pubmed/20696863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904046 |
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