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Separate Roles for Antigen Recognition and Lymph Node Inflammation in CD8(+) Memory T Cell Formation

Priming of naive CD8(+) T cells by pathogens or vaccines generally involves their interaction with Ag-loaded dendritic cells (DCs) in the context of an inflamed lymph node. Lymph node activation fosters DC and T cell encounters and subsequently provides newly primed T cells with nurturing conditions...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fransen, Marieke F., van Stipdonk, Marianne J., Sluijter, Marjolein, Schoenberger, Stephen P., Melief, Cornelis J., Offringa, Rienk
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388546/
https://ncbi.nlm.nih.gov/pubmed/20696863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904046
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