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Dynamic force-induced direct dissociation of protein complexes in a nuclear body in living cells

Despite past progress in understanding mechanisms of cellular mechanotransduction, it is unclear whether a local surface force can directly alter nuclear functions without intermediate biochemical cascades. Here we show that a local dynamic force via integrins resulted in direct displacements of coi...

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Autors principals: Poh, Yeh-Chuin, Shevtsov, Sergey P., Chowdhury, Farhan, Wu, Douglas C., Na, Sungsoo, Dundr, Miroslav, Wang, Ning
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388544/
https://ncbi.nlm.nih.gov/pubmed/22643893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1873
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