Figitumumab combined with carboplatin and paclitaxel in treatment-naïve Japanese patients with advanced non-small cell lung cancer

Objectives The insulin-like growth factor (IGF) signaling pathway has been implicated in the pathogenesis of numerous tumor types, including non-small cell lung cancer (NSCLC). Figitumumab is a fully human IgG2 monoclonal antibody against IGF-1 receptor (IGF-1R). Methods This phase I, open-label, do...

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Dettagli Bibliografici
Autori principali: Goto, Yasushi, Sekine, Ikuo, Tanioka, Maki, Shibata, Takashi, Tanai, Chiharu, Asahina, Hajime, Nokihara, Hiroshi, Yamamoto, Noboru, Kunitoh, Hideo, Ohe, Yuichiro, Kikkawa, Hironori, Ohki, Emiko, Tamura, Tomohide
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2011
Soggetti:
Phase I Studies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388259/
https://ncbi.nlm.nih.gov/pubmed/21748299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-011-9715-4
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