Weak Interactions Govern the Viscosity of Concentrated Antibody Solutions: High-Throughput Analysis Using the Diffusion Interaction Parameter

Weak protein-protein interactions are thought to modulate the viscoelastic properties of concentrated antibody solutions. Predicting the viscoelastic behavior of concentrated antibodies from their dilute solution behavior is of significant interest and remains a challenge. Here, we show that the dif...

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Detaylı Bibliyografya
Asıl Yazarlar: Connolly, Brian D., Petry, Chris, Yadav, Sandeep, Demeule, Barthélemy, Ciaccio, Natalie, Moore, Jamie M.R., Shire, Steven J., Gokarn, Yatin R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2012
Konular:
Molecular Machines, Motors, and Nanoscale Biophysics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388210/
https://ncbi.nlm.nih.gov/pubmed/22828333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.04.047
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