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Toll-Like Receptor 4 Engagement Inhibits Adenosine 5′-Monophosphate–Activated Protein Kinase Activation through a High Mobility Group Box 1 Protein–Dependent Mechanism

Despite the potent antiinflammatory effects of pharmacologically induced adenosine 5′-monophosphate kinase (AMPK) activation on Toll-like receptor 4 (TLR4)-induced cellular activation, there is little evidence that AMPK is activated during inflammatory conditions. In the present studies, we examined...

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Main Authors: Tadie, Jean-Marc, Bae, Hong-Beom, Deshane, Jessy S, Bell, Celeste P, Lazarowski, Eduardo R, Chaplin, David D, Thannickal, Victor J, Abraham, Edward, Zmijewski, Jaroslaw W
格式: Artigo
語言:Inglês
出版: ScholarOne 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388138/
https://ncbi.nlm.nih.gov/pubmed/22396017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00401
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